Nova’s hepatitis B disease (HBV) model accounts for the virus pathophysiology, including viral replication within hepatocytes and antiviral immune response in chronically infected patients. Nova’s chronic hepatitis B model for exploring and predicting efficacy for novel HBV treatments.

Summary

  1. Model description (HBV)
    1. Biological submodels
    2. Drugs that can be tested
    3. Populations of interest
    4. Possible clinical endpoints
  2. Early insights to optimize your trial design

    1. Drug regimen
    2. Combination of treatments
    3. Patient selection

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