Nova’s atopic dermatitis (AD) model accounts for the interplay between the skin barrier and the immune system. It describes the key pathways and biomarkers influencing disease course, including the mechanisms driving the immune response dysregulation, the loss of skin barrier integrity and the perturbation of the skin microbiome.


  1. Model description (AD)
    1. Drugs that can be tested
    2. Populations of interest
    3. Possible clinical endpoints
    4. Biological submodels
  2. Early insights to optimize your trial design

    1. Drug regimen
    2. Combination of treatments
    3. Patient selection


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